Multimodal antioxidant and anti-inflammatory activity of Rauwolfia serpentina root extracts in experimental models

This study demonstrates that *Rauwolfia serpentina* root extracts, particularly cold ethanolic fractions rich in phenolics and flavonoids, exert potent, coordinated antioxidant and anti-inflammatory effects in immune cell models relevant to cardiovascular disease, with the alkaloid reserpine identified as a key mediator that suppresses inflammatory signaling via IKK/NF-κB pathway modulation.

Acharya, S., Das, S. R., Ankari, A. + 1 more2026-02-17📄 plant biology

A Tissue Culture Free Genome Editing Strategy in Plants Using Broad-Host-Range Viral Vectors Derived from Geminiviruses

This study presents a novel, tissue culture-free plant genome editing platform that utilizes the broad-host-range Wheat dwarf India virus (WDIV) and Ageratum yellow leaf curl betasatellite (AYLCB) to efficiently deliver Cas9, Cas12f, and Cas12j nucleases with optimized guide RNA designs, enabling gene editing across a wide range of plant species.

Kumar, J., ALOK, A., Fox, J. + 4 more2026-02-17📄 plant biology

BackBone Builder (B3): A modular Golden Gate standard with a compatible Agrobacterium parts library

The paper introduces BackBone Builder (B3), a modular Golden Gate-based platform utilizing PaqCI to enable the systematic, one-pot assembly of Agrobacterium binary vector backbones from a library of 42 components, thereby establishing a standardized framework for rational vector engineering with demonstrated high efficiency and functionality in both bacterial and plant systems.

De Saeger, J., Vermeersch, M., Aesaert, S. + 2 more2026-02-17📄 plant biology

Unravelling the processes controlling pollen formation and functions with cross-species comparative analysis

This study leverages a comprehensive cross-species comparative analysis of 16,904 RNA-seq samples from 90 plant species to identify conserved and lineage-specific genetic mechanisms governing pollen and anther development, revealing evolutionary patterns in pollen traits and providing experimentally validated insights for future plant reproductive research.

Mutwil, M.2026-02-17📄 plant biology